About Me

I am a PhD candidate in bioinformatics at ShanghaiTech University, working on cancer multi-omics. I received my B.Eng. in bioengineering from Henan University of Technology in 2022, and my research now focuses on the mechanisms of metastasis and recurrence in hepatocellular carcinoma (HCC). By integrating genomics, transcriptomics, and proteomics data from primary and recurrent tumors, I aim to characterize the evolutionary dynamics of cancer cells during metastatic progression and to identify factors driving post-operative recurrence. I am also involved in translational research on esophageal squamous cell carcinoma (ESCC).

I am dedicated to developing and applying data-driven methods to discover novel biomarkers and therapeutic targets, and to building computational resources that make large-scale cancer omics data easier to interpret and reuse.

Research Interests

• Mechanisms of Cancer Metastasis and Recurrence: Investigating the molecular and cellular processes driving cancer metastasis and post-curative-treatment recurrence, with a focus on liver cancer, to identify potential therapeutic targets.

• Single-cell, Multi-omics and Machine Learning: Integrating genomics, transcriptomics, proteomics, and single-cell multi-omics data, and applying machine learning and foundation models — including single-cell, spatial and pathology models — to cell-state representation, tissue phenotyping, and cross-modal analysis of tumor biology and its clinical implications.

• Biomarker Discovery and Translational Research: Identifying novel biomarkers for prognosis and recurrence prediction through multi-omics data and machine-learning based survival modelling, and supporting the development of personalized treatment strategies for liver cancer and other malignancies.